Physician-led metabolic care
Weight loss that gives you your energy back.
Retatrutide — the first triple-pathway medication of its kind — paired with a physician who actually knows your story. For people done with quick fixes and ten-minute visits.
Free eligibility check · No insurance required · Cancel anytime
after a personal health review
Why retatrutide
One medication. Three metabolic pathways.
Most GLP-1 medications act on one or two hormone receptors. Retatrutide is a triple agonist — working with three of your body's own metabolic signals at once, not against them.
GLP-1
Appetite
Reduces appetite and slows digestion — so you feel full sooner, and stay full longer.
GIP
Metabolism
Supports insulin response and how your body processes and stores what you eat.
Glucagon
Energy burn
Increases energy expenditure — the pathway older GLP-1 medications don't reach.
The scale is just the beginning.
How it compares
Beyond first-generation GLP-1s.
Semaglutide activates one receptor. Tirzepatide, two. Retatrutide is the first to engage all three — appetite, metabolism, and energy expenditure together.
Start with retatrutideHealthspan first
Lose the weight. Keep the strength.
Fast weight loss can take muscle with it — and muscle is what carries you through the decades ahead. Your Solstice physician paces your dose deliberately, and your plan protects what matters as the number comes down.
How it works
From first question to first dose — all online.
01
Share your health story
A 5-minute online assessment covering your history, goals, and lifestyle.
02
Baseline metabolic panel
An at-home lab kit establishes your metabolic baseline — real data your physician actually uses.
03
Physician review
A US-licensed physician reviews your assessment and labs, and prescribes if appropriate.
04
Delivered, then dialed in
Medication ships free from a trusted US pharmacy — then regular check-ins and dose adjustments as your body responds.
One simple plan
Everything included. No surprises.
One monthly price covers your medication, your physician, and everything in between. No insurance paperwork, no prior authorizations, no hidden fees, no long-term contracts.
Retatrutide Program
All-inclusive$399/ month
Pause or cancel anytime. No commitments.
For context: branded GLP-1 medications commonly list at $1,000+/month without insurance.
Free eligibility check · HIPAA-secure · No insurance needed
Your care team
Real physicians. Real oversight.
Every Solstice prescription is written by a US-licensed physician after a personal review of your health history — the opposite of the rushed ten-minute visit. Your care doesn't stop at checkout: your team monitors your progress and adjusts your plan as your body responds.
Board-aligned protocols
Clinical guidelines built by our physician group, reviewed continuously.
Licensed in your state
Care is delivered by providers licensed where you live.
Trusted US manufacturing
Medication sourced from vetted, US-based facilities.
HIPAA-secure
Your health information stays private, always.
What members say about the shift.
“For the first time in years, the noise around food is just… quiet.”
Member since 2025
“I finally have the energy to be present with my kids. That's the part no scale measures.”
Member since 2025
“I'm not chasing my twenties. I'm building the next thirty years — and this is the first plan that treats it that way.”
Member since 2026
Individual experiences vary. Members compensated for their time.
Not ready yet?
Start with the guide.
What's actually driving your weight after 40 — a plain-language primer on metabolism, muscle, and the new generation of GLP-1s.
Free. No spam — unsubscribe anytime.
Questions, answered.
Is retatrutide right for me?+
That's exactly what the eligibility check is for. A US-licensed physician reviews your health history, goals, and any medications you take — and only prescribes if it's clinically appropriate for you. If it isn't, you pay nothing.
How is retatrutide different from semaglutide or tirzepatide?+
Semaglutide acts on one hormone receptor (GLP-1) and tirzepatide on two (GLP-1 and GIP). Retatrutide engages three — GLP-1, GIP, and glucagon — adding a pathway associated with energy expenditure that earlier medications don't reach.
What is retatrutide's FDA status?+
A straight answer: retatrutide is an investigational medication in late-stage clinical trials, and there is no FDA-approved version yet. Where Solstice offers it, it is prepared by licensed US compounding pharmacies and prescribed only when a physician determines it's clinically appropriate for you. Your physician will walk through exactly what this means before anything is prescribed — and if you have questions, ask them. We'd rather you understand it than just buy it.
Do I need insurance?+
No. Solstice is priced for direct pay — one flat monthly rate covers your medication, physician care, and shipping. No claims, no prior authorizations, no paperwork.
What's included in the monthly price?+
Everything: your monthly medication, unlimited provider consultations, personalized dose adjustments, free discreet shipping, and ongoing support from your care team.
How do consultations work?+
Entirely online, on your schedule. Message your care team anytime, and connect with your physician for reviews and dose adjustments — no waiting rooms, no time off work.
Can I cancel anytime?+
Yes. There are no contracts or commitments — pause or cancel from your account in a couple of clicks, whenever you choose.
Important safety information
The honest fine print.
Retatrutide is not FDA-approved. It is an investigational medication currently in clinical trials, and there is no FDA-approved retatrutide product. The U.S. Food and Drug Administration (FDA) has not evaluated the statements or products on this page, and nothing here is intended to diagnose, treat, cure, or prevent any disease.
Compounded medications are not FDA-approved. Where treatment is offered, retatrutide is prepared by a U.S. state-licensed compounding pharmacy operating in accordance with cGMP (current Good Manufacturing Practice) standards. Compounded drugs are not reviewed by the FDA for safety, effectiveness, or manufacturing quality before they are dispensed.
A prescription is never guaranteed. Any medication is prescribed only after an online medical evaluation, at the sole discretion of a U.S.-licensed physician who is licensed in your state, and only when clinically appropriate for you. Treatment may involve the off-label use of a medication. Not everyone is a candidate.
This is not medical advice. The information on this page is general and for educational purposes only; it is not a substitute for professional medical advice, diagnosis, or treatment. Always talk with your physician or care team about your health history, current medications, and any risks or side effects before starting, changing, or stopping any treatment. Do not use if you are pregnant, planning to become pregnant, or breastfeeding.
Individual results vary. Weight-loss and health outcomes differ from person to person and are not guaranteed. Any figures, charts, or testimonials shown are illustrative and do not represent a promise of results. If you experience a medical emergency, call 911 or seek immediate in-person care.