Physician-led metabolic care

Weight loss that gives you your energy back.

Retatrutide — the first triple-pathway medication of its kind — paired with a physician who actually knows your story. For people done with quick fixes and ten-minute visits.

Check if I qualify See the science ↓

Free eligibility check · No insurance required · Cancel anytime

warm morning light
Rx Physician-prescribed
after a personal health review
◦ US-licensed physicians ◦ Trusted US manufacturing ◦ No insurance needed ◦ Free, discreet shipping ◦ HIPAA-secure care

Why retatrutide

One medication. Three metabolic pathways.

Most GLP-1 medications act on one or two hormone receptors. Retatrutide is a triple agonist — working with three of your body's own metabolic signals at once, not against them.

GLP-1

Appetite

Reduces appetite and slows digestion — so you feel full sooner, and stay full longer.

GIP

Metabolism

Supports insulin response and how your body processes and stores what you eat.

Glucagon

Energy burn

Increases energy expenditure — the pathway older GLP-1 medications don't reach.

The scale is just the beginning.

Quieter food noise Steadier energy Healthier metabolism Strength for the long run

How it compares

Beyond first-generation GLP-1s.

Semaglutide activates one receptor. Tirzepatide, two. Retatrutide is the first to engage all three — appetite, metabolism, and energy expenditure together.

Start with retatrutide
Pathway Semaglutide Tirzepatide Retatrutide
GLP-1 · appetite
GIP · metabolism
Glucagon · energy burn

Healthspan first

Lose the weight. Keep the strength.

Fast weight loss can take muscle with it — and muscle is what carries you through the decades ahead. Your Solstice physician paces your dose deliberately, and your plan protects what matters as the number comes down.

01 Physician-paced dosing — titrated to your body's response, not a fixed calendar.
02 Protein & strength protocols — simple resistance and nutrition targets built into your plan.
03 Progress beyond the scale — your care team tracks energy, strength, and labs, not just pounds.
strength for the long run

How it works

From first question to first dose — all online.

01

Share your health story

A 5-minute online assessment covering your history, goals, and lifestyle.

02

Baseline metabolic panel

An at-home lab kit establishes your metabolic baseline — real data your physician actually uses.

03

Physician review

A US-licensed physician reviews your assessment and labs, and prescribes if appropriate.

04

Delivered, then dialed in

Medication ships free from a trusted US pharmacy — then regular check-ins and dose adjustments as your body responds.

One simple plan

Everything included. No surprises.

One monthly price covers your medication, your physician, and everything in between. No insurance paperwork, no prior authorizations, no hidden fees, no long-term contracts.

Money-back guarantee — if a physician determines you're not eligible, you pay nothing.

Retatrutide Program

All-inclusive

$399/ month

Pause or cancel anytime. No commitments.

For context: branded GLP-1 medications commonly list at $1,000+/month without insurance.

Retatrutide medication, every month Baseline metabolic lab panel Unlimited provider consultations Personalized dose adjustments Free 2-day discreet shipping Ongoing support from your care team
Check if I qualify

Free eligibility check · HIPAA-secure · No insurance needed

your care team

Your care team

Real physicians. Real oversight.

Every Solstice prescription is written by a US-licensed physician after a personal review of your health history — the opposite of the rushed ten-minute visit. Your care doesn't stop at checkout: your team monitors your progress and adjusts your plan as your body responds.

Board-aligned protocols

Clinical guidelines built by our physician group, reviewed continuously.

Licensed in your state

Care is delivered by providers licensed where you live.

Trusted US manufacturing

Medication sourced from vetted, US-based facilities.

HIPAA-secure

Your health information stays private, always.

Whole-person care

The medication quiets the noise. What you build in that quiet is the point.

Retatrutide creates a window where change feels possible. Your program uses it — with practices guided by your care team, woven in, not bolted on.

Mindful eating

With the noise low, relearn your real hunger and fullness cues — habits that outlast any prescription.

Movement & strength

Simple, sustainable resistance work that protects muscle and builds the body you'll live in next.

Rhythm & recovery

Sleep and stress patterns that hold the change in place — because metabolism doesn't work in isolation.

What members say about the shift.

“For the first time in years, the noise around food is just… quiet.”

S Sarah M.
Member since 2025

“I finally have the energy to be present with my kids. That's the part no scale measures.”

D David R.
Member since 2025

“I'm not chasing my twenties. I'm building the next thirty years — and this is the first plan that treats it that way.”

A Alicia T.
Member since 2026

Individual experiences vary. Members compensated for their time.

Not ready yet?

Start with the guide.

What's actually driving your weight after 40 — a plain-language primer on metabolism, muscle, and the new generation of GLP-1s.

Send the guide

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Questions, answered.

Is retatrutide right for me?+

That's exactly what the eligibility check is for. A US-licensed physician reviews your health history, goals, and any medications you take — and only prescribes if it's clinically appropriate for you. If it isn't, you pay nothing.

How is retatrutide different from semaglutide or tirzepatide?+

Semaglutide acts on one hormone receptor (GLP-1) and tirzepatide on two (GLP-1 and GIP). Retatrutide engages three — GLP-1, GIP, and glucagon — adding a pathway associated with energy expenditure that earlier medications don't reach.

What is retatrutide's FDA status?+

A straight answer: retatrutide is an investigational medication in late-stage clinical trials, and there is no FDA-approved version yet. Where Solstice offers it, it is prepared by licensed US compounding pharmacies and prescribed only when a physician determines it's clinically appropriate for you. Your physician will walk through exactly what this means before anything is prescribed — and if you have questions, ask them. We'd rather you understand it than just buy it.

Do I need insurance?+

No. Solstice is priced for direct pay — one flat monthly rate covers your medication, physician care, and shipping. No claims, no prior authorizations, no paperwork.

What's included in the monthly price?+

Everything: your monthly medication, unlimited provider consultations, personalized dose adjustments, free discreet shipping, and ongoing support from your care team.

How do consultations work?+

Entirely online, on your schedule. Message your care team anytime, and connect with your physician for reviews and dose adjustments — no waiting rooms, no time off work.

Can I cancel anytime?+

Yes. There are no contracts or commitments — pause or cancel from your account in a couple of clicks, whenever you choose.

Your solstice is the turning point.

Find out in minutes whether retatrutide is right for you — reviewed by a physician who reads your whole story, at no cost.

Check if I qualify — free

No insurance required · Cancel anytime